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The Pentose Phosphate Shunt Provides Reducing Equivalents For Reductive Biosynthesis And Maintaining An Intracellular Reducing Environment The activity of the oxidative phase of the pentose phosphate shunt is low in muscle, but high in liver, testis, adrenal cortex, and mammary gland, where NADPH is used in the synthesis of fatty acids or steroids, and in red blood cells, which are exposed to strongly oxidizing conditions as a result of their oxygen carrying function and use NADPH generated by the pentose phosphate shunt to counteract their oxidizing environment

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Theo các bác sĩ, suy thận mạn là một bệnh lý thường được phát hiện muộn do những tổn thương tiến triển âm thầm, hầu hết người bệnh không tự phát hiện được khi suy thận ở mức độ nhẹ